Hexaamminecobalt(III) chloride (evaluation A)

Protocols evaluated by Rita C. C. Duarte, on 2014 / 08

Product applications

Hexaamminecobalt(III) chloride is used in some methods of structural Biology (especially for DNA and RNA).1,2 It is also used as reagent for pyrophosphoric acid, for the estimation of phosphate.3



(1) Kumar, C.V.; Tan, W.B.; Betts, P.W. Hexamminecobalt(III) chloride-assisted, visible light-induced, sequence-dependent cleavage of DNA. J. Inorg. Biochem. 199768, 177-181.

(2) Rüdisser, S.; Tinoco Jr, I. Solution structure of cobalt(III) hexammine complexed to the GAAA tetraloop, and metal-ion binding to G.A mismatches. J. Mol. Biol. 2000295, 1211-1223.

(3) The Merck Index, http://themerckindex.cambridgesoft.com/themerckindex/Forms/Home/ContentArea/Home.aspx (accessed April 2013).