tert-Butyl chloride

Protocols evaluated by Rita C. C. Duarte, on 2014 / 08

Greenness assessment of experimental protocols

(click on the protocol letter for detailed information)
Protocol Steps Global
Reaction Isolation Purification
A

R1

GSAI = 45.00%

I1

GSAI = 33.33%

Pu1

GSAI = 41.67%

G1

GSAI = 30.00%

B

R2

GSAI = 50.00%

I2

GSAI = 33.33%

Pu1

GSAI = 41.67%

G2

GSAI = 30.00%

C

R3

GSAI = 45.00%

I3

GSAI = 50.00%

No purification

G3

GSAI = 45.00%

D

R4

GSAI = 45.00%

I4

GSAI = 33.33%

Pu1

GSAI = 41.67%

G4

GSAI = 30.00%

E

R5

GSAI = 50.00%

I5

GSAI = 33.33%

Pu2

GSAI = 41.67%

G5

GSAI = 30.00%

F

R5

GSAI = 50.00%

I6

GSAI = 50.00%

Pu2

GSAI = 41.67%

G6

GSAI = 40.00%

G

R6

GSAI = 45.00%

I7

GSAI = 25.00%

No purification

G7

GSAI = 35.00%

H

R7

GSAI = 50.00%

I8

GSAI = 50.00%

Pu1

GSAI = 41.67%

G8

GSAI = 40.00%

I

R7

GSAI = 50.00%

I9

GSAI = 33.33%

Pu1

GSAI = 41.67%

G9

GSAI = 30.00%

J

R7

GSAI = 50.00%

I10

GSAI = 50.00%

Pu1

GSAI = 41.67%

G10

GSAI = 40.00%

K

R7

GSAI = 50.00%

I11

GSAI = 50.00%

Pu1

GSAI = 41.67%

G11

GSAI = 40.00%

L

R7

GSAI = 50.00%

I12

GSAI = 33.33%

No purification

G12

GSAI = 40.00%

M

R7

GSAI = 50.00%

I13

GSAI = 50.00%

No purification

G13

GSAI = 50.00%

N

R7

GSAI = 50.00%

I14

GSAI = 33.33%

Pu1

GSAI = 41.67%

G14

GSAI = 30.00%

O

R8

GSAI = 50.00%

I14

GSAI = 33.33%

Pu2

GSAI = 41.67%

G15

GSAI = 30.00%

P

R9

GSAI = 50.00%

I15

GSAI = 50.00%

Pu1

GSAI = 41.67%

G16

GSAI = 40.00%

Q

R10

GSAI = 50.00%

I16

GSAI = 33.33%

No purification

G17

GSAI = 40.00%

R

R11

GSAI = 50.00%

I17

GSAI = 33.33%

Pu1

GSAI = 41.67%

G18

GSAI = 30.00%

S

R12

GSAI = 45.00%

I18

GSAI = 50.00%

Pu1

GSAI = 41.67%

G19

GSAI = 40.00%

T

R13

GSAI = 45.00%

I19

GSAI = 50.00%

Pu1

GSAI = 41.67%

G20

GSAI = 40.00%

U

R14

GSAI = 50.00%

I20

GSAI = 33.33%

Pu1

GSAI = 41.67%

G21

GSAI = 30.00%