Ethyl acetate

Protocols evaluated by Rita C. C. Duarte, on 2014 / 08
Published on Rita C. C. Duarte, M. Gabriela T. C. Ribeiro, Adélio A. S. C. Machado, Using Green Star Metrics To Optimize the Greenness of Literature Protocols for Syntheses, J. Chem. Educ., 92, 1024-1034, 2015.

Product applications

Ethyl acetate is used as organic solvent for nitrocellulose, varnishes and lacquers; in the production of smokeless powder, artificial leather and silk, photographic films and plates, perfumes, cleaning textiles; as an essence in in pharmaceuticals and food;¹ as solvent in chromatography and as reagent and extraction and purification medium of organic products in organic synthesis.^1,2 Mainly used in the electronics, cosmetic, printing, food, coating^3-6 and agrochemical industries.^4,6

References:

(1) The Merck Index, http://themerckindex.cambridgesoft.com/themerckindex/Forms/Home/ContentArea/Home.aspx (accessed April 2013).

(2) Chazin, E.L. Métodos de Preparação Industrial de Solventes e Reagentes Químicos. Rev. Virt. Quím. 2012, 4(6), 872-883.

(3) Solventis, http://www.solventis.net/esters/ethyl-acetate (accessed December 2015).

(4) Rhodia, http://www.rhodia.com/en/binaries/Ethyl_acetate_GPS_rev0_June12_RHD.pdf (accessed May 2013).

(5) ICIS, http://www.icis.com/Articles/2007/11/02/9075320/ethyl-acetate-uses-and-market-data.html (accessed May 2013).

(6) Gurav, H.; Bokade, V.V. Synthesis of ethyl acetate by esterification of acetic acid with ethanol over a heteropolyacid on montmorillonite K10. J. Nat. Gas Chem. 2010, 19, 161-164.